News

Researchers at Stanford have revealed a novel mechanism that breast cancer cells use to physically tear and deform the basement membrane barrier to break out and become invasive.

A model based on artificial intelligence is able to predict the therapy outcome in 80% of ovarian cancer patients. The tool, named IRON (Integrated Radiogenomics for Ovarian Neoadjuvant therapy), analyzes various patient clinical features.

A single master regulator of the genome can be used to reprogram a network of thousands of genes in T cells and greatly enhance cancer cell killing.

New research has uncovered the molecular basis of breast cancer metastasis driven by the MAF protein, opening up the possibility of preventing metastasis.

Researchers suggest that when used in a form that can be delivered directly into the tumor cell, polyinosine–polycytidylic acid (pIC) suppresses tumor growth, induces cancer cell death and enhances survival.

The EPI-CT study, which involved almost one million people, confirms that CT imaging, although largely beneficial, entails a small risk that needs to be minimised as much as possible.

The largest and most diverse investigation into prostate cancer genetics yet, which included major increases in representation among men from different racial and ethnic groups, has revealed 187 new risk variants.

New research has discovered that breast cancer cells expressing the Myc gene rely heavily on vitamin B5 to grow and survive, which could potentially be exploited as a therapeutic avenue.

Recent studies indicate that inflammation is one of the causes of the development of benign prostatic hyperplasia (BPH). Inflammation may result from past infections, but also from the state of functioning of the intestinal microbiota.

Scientists have developed a new method to engineer more powerful immune cells that can potentially be used for “off-the-shelf” cell therapy to treat challenging cancers.