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An Intravenous Needle That Softens in the Body on Insertion
Researchers have developed an intravenous needle that softens and flexes when in the body, reducing the risk of damage to the blood vessel as patients receive medication.
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Men Die 6 Years Before Women in the US
We’ve known for more than a century that women outlive men. But new research shows that, at least in the United States, the gap has been widening for more than a decade.
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Disrupting One Gene in CAR T Cells Makes Them More Potent
Disrupting one gene in CAR T cells used for cancer therapy makes them more potent and able to fight the cancer for longer, reports a new study.
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Existing Drug That Targets Sleeping Cells Could Be the Answer To Lower Back Pain
A study of senescent (inactive) osteoclasts in the vertebral column of mice suggests that using anti-senescent drugs could relieve the spinal sensitivity that causes lower back pain.
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Birth Control Hormones Can Enter the Adolescent Mouse Brain
Ohio State scientists are exploring how common synthetic hormones used for birth control affect the prefrontal cortex, an area of the brain that continues to develop throughout adolescence.
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New Compound Outperforms Pain Drug
A small molecule drug, one of 27 million screened in a library of potential new drugs, has shown promise as a painkiller, outperforming gabapentin for treating four types of chronic pain.
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New Pancreatic Cancer Treatment Approach Shows Promise for Increased Survival
Researchers suggest that when used in a form that can be delivered directly into the tumor cell, polyinosine–polycytidylic acid (pIC) suppresses tumor growth, induces cancer cell death and enhances survival.
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Experimental Treatment Achieves 94% Reduction in Key Heart Disease Marker
A phase 1 trial for Lepodisiran has shown it can reduce levels of lipoprotein A, a key driver of heart disease risk, by 94%, with results lasting for nearly a year.
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New Step in Dietary Cholesterol Processing Opens Treatment Avenues
Researchers have described a previously unknown step in the complex process by which dietary cholesterol is processed in the intestines before being released into the bloodstream – potentially revealing a new pathway to target.
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Liver Cells Age Differently Depending on Where They Are in the Organ
Looking around us, we can see that people age at different rates. But what about inside? Do all cells age in the same way? Researchers have now shown in the liver of mice that liver cells age differently depending on where they are located.
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