Latest Articles

A revolutionary gene therapy has become a transformative treatment for children with metachromatic leukodystrophy (MLD). But substantial barriers to access for this groundbreaking therapy remain.

In this article, we discuss the fundamentals of transfection, provide an overview of some of the commonly employed methods and a sample protocol. Finally, we consider some of the key applications of transfection.

This article will present two multiomics vignettes. One involves the search for a deeper understanding of food allergies and a potential path forward for treatment. Another will describe the response to bariatric surgery, a growing need as obesity trends upward in many parts of the world.

Scientists from the Institute for Systems Biology (ISB) have created a biological BMI, an alternative to the "traditional" approach. Technology Networks interviewed the lead researchers to understand why it could be a useful alternative measure of health.

This article explores new workflows using data-driven modeling to improve culture medium and new control algorithms allowing for better modulation within the bioprocess design space.

Structural biology uses a variety of techniques to determine the 3D structures of biomolecules such as proteins, nucleic acids and their complexes. In this article, we consider the key techniques, their role in structural biology, strengths and limitations.

This article will review advances in multimodal imaging mass spectrometry applications and a computational method to achieve higher resolution from spatial transcriptomics datasets.

Some stories of history are written in ink, and others are written in nucleotide bases. Ancient DNA (aDNA) analysis – the study of DNA from archaeological or paleontological specimens – is perhaps the closest scientists will ever come to a time machine – a window into the past. In this feature article, we explore how inclusion and representation are critical considerations when we look through that window.

This article walks through some of the foundational developments in the field of glycobiology that have powered the progress made in 2022 and what these advancements signal for the future.

In this article, we consider what structural biology tells us and the techniques used to investigate it, the role of computation and how techniques can be used together to answer questions in a range of application areas.