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Promising Antibiotic Breakthrough Unveiled for Lyme Disease

Using a technique that has shown promise in targeting cancer tumors, a Duke Health team has found a way to deploy a molecular warhead that can annihilate the bacterium that causes Lyme disease.
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MicroRNA Could Create Starting Point for New Atherosclerosis Therapy

A specific microRNA molecule has been identified as a promising starting point for the investigation of new therapies for atherosclerosis.
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Radiopharmaceutical Shows Early Promise in Prostate Cancer Trial

Researchers at Weill Cornell Medicine have led a phase 1 trial of a new drug that delivers potent radiation therapy directly and specifically to cancer cells in patients with advanced prostate cancer.
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Charged “Molecular Beasts” as the Basis for New Compounds

Charged, chemically "aggressive" fragments could be the basis for synthesizing new compounds with unreactive elements that could be used for microchips and solar cells.
A zebrafish.
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Understanding the Neural Circuits That Control the Speed of Locomotion

Researchers at Karolinska Institutet, Sweden have uncovered the molecular logic underpinning the assembly of spinal circuits that control the speed of locomotion in adult zebrafish.
A person holds a pink breast cancer ribbon.
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Potential Targets Identified for Therapy-Resistant Breast Cancers

Researchers have identified potential targets to treat therapy-resistant breast cancers, suggesting some already-approved drugs could be repurposed for certain cancer patients.
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Mechanism Behind Aspirin’s Protective Effect Against Colorectal Cancer Identified

Aspirin has been shown to reduce colorectal cancer risk and inhibit cancer progression. A new study has revealed the molecular mechanisms behind these effects.
A month's supply of the contraceptive pill in its blister packet.
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Why Are Former Contraceptive Pill Users More Likely to Report Depression?

A new study has shown that women who are taking the oral contraceptive pill are less likely to report depression, compared to former users of the pill.
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Two Methods Simplify Atom Swapping in Drug Development

The development of two new methods to swap carbon atoms for nitrogen atoms in drug molecules – a common problem in pharmaceutical chemistry – could make it easier to develop new drugs.
Double helix structure of DNA.
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Researchers Identify Metabolite That Tells Cells Whether To Repair DNA

Researchers have figured out how a specific metabolite controls the activity of DNA repair and how sensitive tissues are to cancer treatment.
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