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Cell Culture – News and Features

Human microglia implanted in the hippocampus region of the brain of a mouse.
News

Mutant Immune Cells in the Brain Heighten Alzheimer's Risk

A new MIT study finds that microglia with mutant TREM2 protein reduce brain circuit connections, promote inflammation and contribute to Alzheimer’s pathology in other ways.
Cell structure.
News

Molecular Glue Degraders Could Target “Undruggable” Proteins

Cells contain molecular machinery that targets and disposes of unwanted proteins. Scientists would like to hijack this process to control proteins involved in cancer and other diseases, using a type of molecule called a molecular glue degrader.
A scientist loading samples into a microwell plate.
Article

Advances in CHO Cell Line Development for Biotherapeutics

A diverse array of biological medicines are now used to prevent and treat a wide range of illnesses. This article will discuss the development of cell lines in biopharma and will touch on key considerations, such as future manufacturability.
A scientist in a lab.
News

Improved Research Models for Parkinson’s Disease Created

Researchers developed an improved method to study Parkinson’s disease in the lab. Along the way, researchers also uncovered clues that may help scientists figure out how to detect Parkinson’s earlier and point the way toward better treatments.
A shark.
News

Sharks Possess “Surprising” Bitter Taste Perception

Researchers from the University of Cologne discovered that sharks possess the same receptors that humans use to perceive bitter taste.
Cancer cells.
News

Cancer Stem Cells Trigger Macrophage Aging

Cancer stem cells cause the aging of macrophages in mice with healthy immune systems, creating conditions for the formation of tumors.
A microscope image of breast cancer cells. MHC 1 is shown in red and the nuclei in blue.
News

Breast Cancer Cells Collaborate To Invade Surrounding Tissue

Researchers at Stanford have revealed a novel mechanism that breast cancer cells use to physically tear and deform the basement membrane barrier to break out and become invasive.
A cynomolgus monkey.
News

World’s First Chimeric Monkey Born Using Embryonic Stem Cells

Chinese scientists report the first birth of a live chimeric monkey whose cells largely derive from a line of monkey stem cells. Their findings are published in Cell.
A bacteriophage.
News

What Happens in a Virus Particle When the Temperature Is Raised?

Researchers at Lund University, together with colleagues at the NIST Synchrotron Facility in the USA, have mapped on an atomic level what happens in a virus particle when the temperature is raised.
A close-up image of a fly on a white surface.
News

Potential Anti-Cancer Target Identified in Flies

MYC proteins play an important role in many types of cancer. A research team at the University of Würzburg has now succeeded in indirectly influencing these proteins – with clear consequences for the tumor.
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