Gene and Cell Therapy – News and Features

Traditional bone marrow aspirate (BMA) stem cell extraction methods are complex, time-consuming, and yield poor results due to antiquated centrifugation techniques.

Macrophages, a type of white blood cell that can destroy invading pathogens, have an innate ability to infiltrate tumor cells, making them a potentially important tool in treatments that use transplanted cells to fight disease, known as cell therapy.

Disrupting one gene in CAR T cells used for cancer therapy makes them more potent and able to fight the cancer for longer, reports a new study.

Andrew Schulman explores why we need allogeneic therapies, the importance of collaboration to keep the momentum, and challenges and predictions for the future.

A single master regulator of the genome can be used to reprogram a network of thousands of genes in T cells and greatly enhance cancer cell killing.

Mucosal-associated invariant T (MAIT) cells don't obey the usual immune cell rules, and new research has revealed another "superpower" of this cell type.

In 2021, a University-led research team received a contract worth up to $33 million to develop an implantable “living pharmacy” to control the human body’s sleep/wake cycles. Now, the researchers have completed a major step toward achieving this.

Researchers at Lund University, together with colleagues at the NIST Synchrotron Facility in the USA, have mapped on an atomic level what happens in a virus particle when the temperature is raised.

Scientists have developed a new method to engineer more powerful immune cells that can potentially be used for “off-the-shelf” cell therapy to treat challenging cancers.

Researchers at the University of Freiburg have now been able to prevent the exhaustion caused by CAR-T cell therapy and thus significantly improve the effect of the therapy in a preclinical animal model.