Neurodegeneration – News and Features

The way in which nanoplastics and a specific brain protein, α-synuclein, interact could create changes in the body that give rise to Parkinson’s disease (PD) and other related dementias, a new study suggests.

A new MIT study finds that microglia with mutant TREM2 protein reduce brain circuit connections, promote inflammation and contribute to Alzheimer’s pathology in other ways.

Researchers have shed new light on the cellular processes behind Parkinson's and illustrated how disease progression can be halted in a mouse model.

Shrinkage in the hippocampus area of the brain is associated with cognitive decline, even in people who don’t have amyloid plaques in the brain, reports new research.

Researchers developed an improved method to study Parkinson’s disease in the lab. Along the way, researchers also uncovered clues that may help scientists figure out how to detect Parkinson’s earlier and point the way toward better treatments.

For the first time, University of Queensland (UQ) researchers have shown how the tau protein, known for its role in dementias, behaves where communication in the brain takes place.

Researchers at the Buck Institute have identified a new drug-like molecule that keeps mitochondria healthy via mitophagy, a process that removes and recycles damaged mitochondria in multicellular organisms.

A pair of recent studies have uncovered novel cellular mechanisms that are involved in two types of genetic amyotrophic lateral sclerosis, or ALS. The findings improve the understanding of ALS.

An international team of researchers has developed a handheld, non-invasive device that can detect biomarkers for Alzheimer’s and Parkinson’s Diseases.

Is strength training responsible for mitigating the risks of a high-protein diet in althletes? A new study, published in eLife, suggests it might be.