Neurogenomics – News and Features

A new MIT study finds that microglia with mutant TREM2 protein reduce brain circuit connections, promote inflammation and contribute to Alzheimer’s pathology in other ways.

A surprising thing happened when researchers began exploring whether early-life stress compounds the effects of a childhood head injury on health and behavior later in life.

Researchers have identified potential targets to treat therapy-resistant breast cancers, suggesting some already-approved drugs could be repurposed for certain cancer patients.

For centuries, naturalists have puzzled over what might constitute the head of a sea star, commonly called a “starfish.” Researchers have published a study finding that the truth is closer to the absolute reverse.

An early phase in the process of developing Alzheimer’s disease is a metabolic increase in a part of the brain called the hippocampus, report researchers from Karolinska Institutet in a study published in Molecular Psychiatry.

A pioneering study unveiled that the 3D organization of DNA can influence the progression of the aggressive brain tumour known as glioblastoma. Having identified the factors that glioblastoma uses to respond to neurons by growing and spreading.

Organoids help researchers understand biological processes in health and in disease. It is, however, difficult to influence the way in which they organize themselves into complex tissues. Now a group has found a new way to do so.

The gene therapy landscape is dynamic and constantly shifting. In this article, we will review major advances in disease modification for illnesses that presently still lack effective treatments, as well as some challenges and approaches to overcome them.

Researchers at Kyushu University have discovered that turning brain immune cells into neurons successfully restores brain function after stroke-like injury in mice.

Skin organoids offer a powerful platform for drug discovery in the ongoing fight against the virus formerly known as monkeypox.