Structural Biology – Webinars and Online Events
Webinar
Novel Protein Characterization for Biopharma Development
On-Demand
Protein stability is one of the most important critical quality attributes for a new biological drug. Unstable or misfolded proteins are prone to aggregation and precipitation, which can lead to lower activity as well as increased immunogenicity. There has been a long-standing interest in renaturing unfolded, misfolded or precipitated proteins.
In this webinar, our expert speakers will demonstrate how thermal and pressure stress changed the structure and melting point of two model proteins and resulted in the discovery of different structural rearrangements.
They will then discuss a novel method for solubilizing and refolding proteins using hydrostatic pressure to generate proteins whose structure matches that of the native protein, as confirmed by microfluidic modulation spectroscopy.
In this webinar, our expert speakers will demonstrate how thermal and pressure stress changed the structure and melting point of two model proteins and resulted in the discovery of different structural rearrangements.
They will then discuss a novel method for solubilizing and refolding proteins using hydrostatic pressure to generate proteins whose structure matches that of the native protein, as confirmed by microfluidic modulation spectroscopy.
Webinar
Machine Learning Methods for De Novo Antibody Design
On-Demand
In this webinar, our expert speaker Dr. Phillip Kim from the University of Toronto will be discussing the ML methods he currently implements in his lab that enables de novo antibody design. He will also cover ML-based sequence design and scoring methods, as well as diffusion models.
Webinar
The Importance of High-Resolution Ion Mobility Mass Spectrometry to Accurately Read Back the Complex Language of Biology
On-Demand
This webinar discusses an analytical approach for N-linked glycan analysis using the SLIM-based high-resolution ion mobility platform MOBIE. Results will be shown for each aspect of the overall strategy and how this platform can be an integral part for the characterization of protein therapeutics.
Webinar
Genomic Atlas of the Human Proteome and Neurological Disorders
On-Demand
Understanding the tissue-specific genetic architecture of protein levels is instrumental to understand the biology of health and disease.
Webinar
Channelopathies Resolved via Cryo-EM and X-Ray Crystallography
On-Demand
Attend this webinar to learn how Dr. Filip Van Petege's lab is solving crystal structures of isolated RyR domains in wild type and disease mutant forms, exploring excessive phosphorylation of RyRs as well as investigating the mechanical coupling between CaV1.1 and RyR1 in skeletal muscle.
Webinar
Fast and Reliable Gene Synthesis For Optimized Protein Expression
On-Demand
Watch this webinar to discover the benefits of gene synthesis, how gene optimization boosts expression of your protein as well as the fastest and easiest way to assemble your DNA constructs.
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